04 July 1997
Vol 277, Issue 5322

About The Cover

Colony of Candida albicans carrying a deletion of the TUP1 gene. This pathogenic yeast normally switches between single-cell and filamentous states, and both forms are found in its infected mammalian hosts. The tup1 deletion mutant strain grows exclusively as filaments, as seen here on a plate of low-nutrient medium (the width of the field is ~200 micrometers). See 105 and the related Perspective on 52. [Image: Burkhard R. Braun and Alexander D. Johnson]