15 August 1997
Vol 277, Issue 5328

About The Cover

Lymphocyte migrating through a 3-micrometer pore of a filter (green) and making close contact with a monolayer of cultured human intestinal cells (blue). Culturing of these intestinal epithelial cells with Peyer's patch lymphocytes led to the differentiation of the cell monolayer into M cells, specialized cells that transport particles and bacteria from the interior of the gut to the lymphoid tissue. See 949 and the related Perspective on 910. [Image: G. Fischer and L. Lafitte]