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Transgenic Knockout Mice with Exclusively Human Sickle Hemoglobin and Sickle Cell Disease

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Science  31 Oct 1997:
Vol. 278, Issue 5339, pp. 876-878
DOI: 10.1126/science.278.5339.876

Article Information

vol. 278 no. 5339 876-878

PubMed: 
Print ISSN: 
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History: 
  • Received for publication June 13, 1997
  • Accepted for publication September 18, 1997
  • .

Author Information

  1. Chris Pászty*,
  2. Catherine M. Brion,
  3. Elizabeth Manci,
  4. H. Ewa Witkowska,
  5. Mary E. Stevens,
  6. Narla Mohandas,
  7. Edward M. Rubin
  1. C. Pászty and N. Mohandas, Human Genome Center and Department of Subcellular Structure, Lawrence Berkeley National Laboratory, 1 Cyclotron Road (MS 74-157), University of California, Berkeley, CA 94720, USA.
  2. C. M. Brion, M. E. Stevens, E. M. Rubin, Human Genome Center, Lawrence Berkeley National Laboratory, University of California, Berkeley, CA 94720, USA.
  3. E. Manci, Centralized Pathology Unit for Sickle Cell Disease, University of South Alabama Doctors Hospital, Mobile, AL 36604, USA.
  4. H. E. Witkowska, Children's Hospital Oakland Research Institute, Oakland, CA 94609, USA.

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