Molecular Analysis of Cellulose Biosynthesis in Arabidopsis

See allHide authors and affiliations

Science  30 Jan 1998:
Vol. 279, Issue 5351, pp. 717-720
DOI: 10.1126/science.279.5351.717

You are currently viewing the abstract.

View Full Text

Log in to view the full text

Log in through your institution

Log in through your institution


Cellulose, an abundant, crystalline polysaccharide, is central to plant morphogenesis and to many industries. Chemical and ultrastructural analyses together with map-based cloning indicate that the RSW1 locus of Arabidopsis encodes the catalytic subunit of cellulose synthase. The cloned gene complements the rsw1 mutant whose temperature-sensitive allele is changed in one amino acid. The mutant allele causes a specific reduction in cellulose synthesis, accumulation of noncrystalline β-1,4-glucan, disassembly of cellulose synthase, and widespread morphological abnormalities. Microfibril crystallization may require proper assembly of the RSW1 gene product into synthase complexes whereas glucan biosynthesis per se does not.

  • * To whom correspondence should be addressed at Plant Cell Biology Group, Research School of Biological Sciences, Australian National University, Post Office Box 475, Canberra, ACT 2601, Australia. E-mail: richard{at}

View Full Text

Stay Connected to Science