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Aspirin-like Molecules that Covalently Inactivate Cyclooxygenase-2

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Science  22 May 1998:
Vol. 280, Issue 5367, pp. 1268-1270
DOI: 10.1126/science.280.5367.1268

Article Information

vol. 280 no. 5367 1268-1270

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History: 
  • Received for publication September 26, 1997
  • Accepted for publication April 6, 1998

Author Information

  1. Amit S. Kalgutkar,
  2. Brenda C. Crews,
  3. Scott W. Rowlinson,
  4. Carlos Garner*,
  5. Karen Seibert,
  6. Lawrence J. Marnett
  1. A. S. Kalgutkar, B. C. Crews, S. W. Rowlinson, C. Garner, L. J. Marnett, A. B. Hancock Jr. Memorial Laboratory for Cancer Research, Vanderbilt Cancer Center, Center in Molecular Toxicology, Departments of Biochemistry and Chemistry, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
  2. K. Seibert, Searle/Monsanto, 800 North Lindbergh (T3G), St. Louis, MO 63167, USA.

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