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Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

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Science  11 Dec 1998:
Vol. 282, Issue 5396, pp. 2085-2088
DOI: 10.1126/science.282.5396.2085

Article Information

vol. 282 no. 5396 2085-2088

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication September 30, 1998
  • Accepted for publication November 3, 1998
  • .

Author Information

  1. Alexander Poltorak,
  2. Xiaolong He*,
  3. Irina Smirnova,
  4. Mu-Ya Liu,
  5. Christophe Van Huffel,
  6. Xin Du,
  7. Dale Birdwell,
  8. Erica Alejos,
  9. Maria Silva,
  10. Chris Galanos,
  11. Marina Freudenberg,
  12. Paola Ricciardi-Castagnoli,
  13. Betsy Layton,
  14. Bruce Beutler§
  1. A. Poltorak, X. He, I. Smirnova, M.-Y. Liu, C. Van Huffel, X. Du, D. Birdwell, E. Alejos, M. Silva, B. Layton, B. Beutler, Howard Hughes Medical Institute and the Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75235–9050 USA. C. Galanos and M. Freudenberg, Max-Planck Institute für Immunobiologie, Freiburg, Germany. P. Ricciardi, CNR–Cellular and Molecular Pharmacology Center, Milan, Italy.
  1. §To whom correspondence should be addressed at Howard Hughes Medical Institute, 5323 Harry Hines Boulevard, Dallas, TX 75235–9050, USA.

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