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Impaired B Cell Development and Proliferation in Absence of Phosphoinositide 3-Kinase p85α

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Science  15 Jan 1999:
Vol. 283, Issue 5400, pp. 393-397
DOI: 10.1126/science.283.5400.393

Article Information

vol. 283 no. 5400 393-397

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication August 6, 1998
  • Accepted for publication December 17, 1998
  • .

Author Information

  1. David A. Fruman*,
  2. Scott B. Snapper,
  3. Claudine M. Yballe,
  4. Laurie Davidson,
  5. Jonathan Y. Yu,
  6. Frederick W. Alt,
  7. Lewis C. Cantley
  1. D. A. Fruman. C. M. Yballe, J. Y. Yu, L. C. Cantley, Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, MA 02215, and Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA. S. B. Snapper, Department of Medicine, Harvard Medical School, Boston, MA 02115; Howard Hughes Medical Institute, Children's Hospital, Boston, MA 02115; Center for Blood Research, Boston, MA 02115; and Gastrointestinal Unit (Medical Services), Massachusetts General Hospital, Boston, MA 02114, USA. L. Davidson, Howard Hughes Medical Institute, Children's Hospital, Boston, MA 02115, USA. F. W. Alt, Department of Genetics, Harvard Medical School, Boston, MA 02115; Howard Hughes Medical Institute, Children's Hospital, Boston, MA 02115; and Center for Blood Research, Boston, MA 02115, USA.

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