Exon Shuffling in Retrospect

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Science  05 Mar 1999:
Vol. 283, Issue 5407, pp. 1465-1467
DOI: 10.1126/science.283.5407.1465

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Retrotransposons are mobile elements that move through the genome by reverse transcription of their RNA template. In his Perspective, Tom Eickbush discusses new findings reported in this issue by Moran and colleagues that suggest that the insertion of retrotransposable elements in the genome can be beneficial rather than deleterious as previously assumed.