SITE VISIT: Alzheimer's Roundtable

See allHide authors and affiliations

Science  26 Nov 1999:
Vol. 286, Issue 5445, pp. 1643
DOI: 10.1126/science.286.5445.1643c

Alzheimer's disease is one of neuroscience's murkiest pictures, but a Web site devoted to the dreaded killer is remarkably crisp and clear. Among its valuable resources, the Alzheimer Research Forum offers a guide to drugs in clinical trials, links to Alzheimer's-related patents, live panel discussions of hypotheses in vogue, and audio recordings of conference presentations. You'll also find abstracts from milestone papers dating all the way back to Alois Alzheimer's landmark description in 1907 of a 51-year-old woman's decline into dementia and the fibrous tangles later found in her brain during an autopsy.

The forum's in-depth interviews with individual top scientists plumb some of today's biggest puzzles in Alzheimer research. The interviewer, also an Alzheimer researcher, poses a standard slate of questions, asking subjects to describe their working hypotheses about the cause of Alzheimer's disease, speculate about the relentless march of molecular changes that results in dementia, fantasize about experiments to test current theories, and discuss strategies for future treatments. From there the Q&A heads off in directions charted in part by the site's visitors.

The forum solicits feedback on almost every feature of the site. Besides posting questions for future interviews, visitors can vote on which papers deserve “milestone” status and suggest topics for panel discussions or journal clubs before jumping into the fray themselves.

Stay Connected to Science

Navigate This Article