Molecular Rotary Motors

See allHide authors and affiliations

Science  26 Nov 1999:
Vol. 286, Issue 5445, pp. 1687-1688
DOI: 10.1126/science.286.5445.1687

You are currently viewing the summary.

View Full Text

Log in to view the full text

Log in through your institution

Log in through your institution


ATP is the energy currency of the cell: hydrolysis of ATP into ADP and inorganic phosphate (P) releases energy. The enzyme responsible for generating this energy currency is the ATP synthase. In a Perspective, Fillingame discusses two new reports ( Sambongi et al. and Stock et al. ) that present an elegant structural model of how ATP synthase works: it behaves like a tiny molecular rotary motor, coupling the mechanical force of an electrochemical proton gradient to the formation of the chemical bond between ADP and P.