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Perforin Gene Defects in Familial Hemophagocytic Lymphohistiocytosis

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Science  03 Dec 1999:
Vol. 286, Issue 5446, pp. 1957-1959
DOI: 10.1126/science.286.5446.1957

Article Information

vol. 286 no. 5446 1957-1959

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Print ISSN: 
Online ISSN: 
History: 
  • Received for publication September 7, 1999
  • Accepted for publication October 27, 1999
  • .

Author Information

  1. Susan E. Stepp1,
  2. Rémi Dufourcq-Lagelouse2,
  3. Françoise Le Deist2,3,
  4. Sadhna Bhawan1,
  5. Stéphanie Certain2,
  6. Porunelloor A. Mathew4,
  7. Jan-Inge Henter5,
  8. Michael Bennett1,
  9. Alain Fischer2,3,
  10. Geneviève de Saint Basile2,*,,
  11. Vinay Kumar1,*
  1. 1 Department of Pathology and the Graduate Program in Immunology, University of Texas Southwestern Medical School, Dallas, TX 75235, USA.
  2. 2 Unité de Recherches sur le Dévelopment Normal et Pathologique du Système Immunitaire INSERM U429, 75015 Paris, France.
  3. 3 Unité d'Immunologie et d'Hématologie Pédiatrique, Hôpital Necker-Enfants Malades, 75015 Paris, France.
  4. 4 Department of Molecular Biology and Immunology, University of North Texas Health Science Center, Fort Worth, TX 76107, USA.
  5. 5 Child Cancer Research, Karolinska Institutet, Department of Pediatric Hematology and Oncology, Karolinska Hospital, Stockholm S-17177, Sweden.

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