Activation Tagging of the Floral Inducer FT

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Science  03 Dec 1999:
Vol. 286, Issue 5446, pp. 1962-1965
DOI: 10.1126/science.286.5446.1962

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FLOWERING LOCUS T (FT), which acts in parallel with the meristem-identity geneLEAFY (LFY) to induce flowering of Arabidopsis, was isolated by activation tagging. Like LFY, FT acts partially downstream of CONSTANS (CO), which promotes flowering in response to long days. Unlike many other floral regulators, the deduced sequence of the FT protein does not suggest that it directly controls transcription or transcript processing. Instead, it is similar to the sequence of TERMINAL FLOWER 1 (TFL1), an inhibitor of flowering that also shares sequence similarity with membrane-associated mammalian proteins.

  • * These authors contributed equally to this work.

  • Present address: Plant Gene Expression Center, 800 Buchanan Street, Albany, CA 94710, USA.

  • Present address: Dow AgroSciences, LLC, 9330 Zionsville Road, Indianapolis, IN 46268, USA.

  • § Present address: Akkadix Corporation, 11099 North Torrey Pines Road, La Jolla, CA 92037, USA.

  • || To whom correspondence should be addressed. E-mail: weigel{at}

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