Mitochondrial FtsZ in a Chromophyte Alga

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Science  18 Feb 2000:
Vol. 287, Issue 5456, pp. 1276-1279
DOI: 10.1126/science.287.5456.1276

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A homolog of the bacterial cell division gene ftsZ was isolated from the alga Mallomonas splendens. The nuclear-encoded protein (MsFtsZ-mt) was closely related to FtsZs of the α-proteobacteria, possessed a mitochondrial targeting signal, and localized in a pattern consistent with a role in mitochondrial division. Although FtsZs are known to act in the division of chloroplasts, MsFtsZ-mt appears to be a mitochondrial FtsZ and may represent a mitochondrial division protein.

  • * To whom correspondence should be addressed. E-mail: plbeech{at}

  • Present address: Ludwig Institute for Cancer Research, Royal Melbourne Hospital, 3050, Australia.

  • Present address: The Scripps Research Institute, 11055 North Torrey Pines Road, La Jolla, CA 92037, USA.

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