Review

The Genome Sequence of Drosophila melanogaster

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Science  24 Mar 2000:
Vol. 287, Issue 5461, pp. 2185-2195
DOI: 10.1126/science.287.5461.2185

Article Information

vol. 287 no. 5461 2185-2195

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Author Information

  1. Mark D. Adams1,*,
  2. Susan E. Celniker2,
  3. Robert A. Holt1,
  4. Cheryl A. Evans1,
  5. Jeannine D. Gocayne1,
  6. Peter G. Amanatides1,
  7. Steven E. Scherer3,
  8. Peter W. Li1,
  9. Roger A. Hoskins2,
  10. Richard F. Galle2,
  11. Reed A. George2,
  12. Suzanna E. Lewis4,
  13. Stephen Richards2,
  14. Michael Ashburner5,
  15. Scott N. Henderson1,
  16. Granger G. Sutton1,
  17. Jennifer R. Wortman1,
  18. Mark D. Yandell1,
  19. Qing Zhang1,
  20. Lin X. Chen1,
  21. Rhonda C. Brandon1,
  22. Yu-Hui C. Rogers1,
  23. Robert G. Blazej2,
  24. Mark Champe2,
  25. Barret D. Pfeiffer2,
  26. Kenneth H. Wan2,
  27. Clare Doyle2,
  28. Evan G. Baxter2,
  29. Gregg Helt6,
  30. Catherine R. Nelson4,
  31. George L. Gabor,
  32. Miklos7,
  33. Josep F. Abril8,
  34. Anna Agbayani2,
  35. Hui-Jin An1,
  36. Cynthia Andrews-Pfannkoch1,
  37. Danita Baldwin1,
  38. Richard M. Ballew1,
  39. Anand Basu1,
  40. James Baxendale1,
  41. Leyla Bayraktaroglu9,
  42. Ellen M. Beasley1,
  43. Karen Y. Beeson1,
  44. P. V. Benos10,
  45. Benjamin P. Berman2,
  46. Deepali Bhandari1,
  47. Slava Bolshakov11,
  48. Dana Borkova12,
  49. Michael R. Botchan13,
  50. John Bouck3,
  51. Peter Brokstein4,
  52. Phillipe Brottier14,
  53. Kenneth C. Burtis15,
  54. Dana A. Busam1,
  55. Heather Butler16,
  56. Edouard Cadieu17,
  57. Angela Center1,
  58. Ishwar Chandra1,
  59. J. Michael Cherry18,
  60. Simon Cawley19,
  61. Carl Dahlke1,
  62. Lionel B. Davenport1,
  63. Peter Davies1,
  64. Beatriz de Pablos20,
  65. Arthur Delcher1,
  66. Zuoming Deng1,
  67. Anne Deslattes Mays1,
  68. Ian Dew1,
  69. Suzanne M. Dietz1,
  70. Kristina Dodson1,
  71. Lisa E. Doup1,
  72. Michael Downes21,
  73. Shannon Dugan-Rocha3,
  74. Boris C. Dunkov22,
  75. Patrick Dunn1,
  76. Kenneth J. Durbin3,
  77. Carlos C. Evangelista1,
  78. Concepcion Ferraz23,
  79. Steven Ferriera1,
  80. Wolfgang Fleischmann5,
  81. Carl Fosler1,
  82. Andrei E. Gabrielian1,
  83. Neha S. Garg1,
  84. William M. Gelbart9,
  85. Ken Glasser1,
  86. Anna Glodek1,
  87. Fangcheng Gong1,
  88. J. Harley Gorrell3,
  89. Zhiping Gu1,
  90. Ping Guan1,
  91. Michael Harris1,
  92. Nomi L. Harris2,
  93. Damon Harvey4,
  94. Thomas J. Heiman1,
  95. Judith R. Hernandez3,
  96. Jarrett Houck1,
  97. Damon Hostin1,
  98. Kathryn A. Houston2,
  99. Timothy J. Howland1,
  100. Ming-Hui Wei1,
  101. Chinyere Ibegwam1,
  102. Mena Jalali1,
  103. Francis Kalush1,
  104. Gary H. Karpen21,
  105. Zhaoxi Ke1,
  106. James A. Kennison24,
  107. Karen A. Ketchum1,
  108. Bruce E. Kimmel2,
  109. Chinnappa D. Kodira1,
  110. Cheryl Kraft1,
  111. Saul Kravitz1,
  112. David Kulp6,
  113. Zhongwu Lai1,
  114. Paul Lasko25,
  115. Yiding Lei1,
  116. Alexander A. Levitsky1,
  117. Jiayin Li1,
  118. Zhenya Li1,
  119. Yong Liang1,
  120. Xiaoying Lin26,
  121. Xiangjun Liu1,
  122. Bettina Mattei1,
  123. Tina C. McIntosh1,
  124. Michael P. McLeod3,
  125. Duncan McPherson1,
  126. Gennady Merkulov1,
  127. Natalia V. Milshina1,
  128. Clark Mobarry1,
  129. Joe Morris6,
  130. Ali Moshrefi2,
  131. Stephen M. Mount27,
  132. Mee Moy1,
  133. Brian Murphy1,
  134. Lee Murphy28,
  135. Donna M. Muzny3,
  136. David L. Nelson3,
  137. David R. Nelson29,
  138. Keith A. Nelson1,
  139. Katherine Nixon2,
  140. Deborah R. Nusskern1,
  141. Joanne M. Pacleb2,
  142. Michael Palazzolo2,
  143. Gjange S. Pittman1,
  144. Sue Pan1,
  145. John Pollard1,
  146. Vinita Puri1,
  147. Martin G. Reese4,
  148. Knut Reinert1,
  149. Karin Remington1,
  150. Robert D. C. Saunders30,
  151. Frederick Scheeler1,
  152. Hua Shen3,
  153. Bixiang Christopher Shue1,
  154. Inga Sidén-Kiamos11,
  155. Michael Simpson1,
  156. Marian P. Skupski1,
  157. Tom Smith1,
  158. Eugene Spier1,
  159. Allan C. Spradling31,
  160. Mark Stapleton2,
  161. Renee Strong1,
  162. Eric Sun1,
  163. Robert Svirskas32,
  164. Cyndee Tector1,
  165. Russell Turner1,
  166. Eli Venter1,
  167. Aihui H. Wang1,
  168. Xin Wang1,
  169. Zhen-Yuan Wang1,
  170. David A. Wassarman33,
  171. George M. Weinstock3,
  172. Jean Weissenbach14,
  173. Sherita M. Williams1,
  174. Trevor Woodage1,
  175. Kim C. Worley3,
  176. David Wu1,
  177. Song Yang2,
  178. Q. Alison Yao1,
  179. Jane Ye1,
  180. Ru-Fang Yeh19,
  181. Jayshree S. Zaveri1,
  182. Ming Zhan1,
  183. Guangren Zhang1,
  184. Qi Zhao1,
  185. Liansheng Zheng1,
  186. Xiangqun H. Zheng1,
  187. Fei N. Zhong1,
  188. Wenyan Zhong1,
  189. Xiaojun Zhou3,
  190. Shiaoping Zhu1,
  191. Xiaohong Zhu1,
  192. Hamilton O. Smith1,
  193. Richard A. Gibbs3,
  194. Eugene W. Myers1,
  195. Gerald M. Rubin34,
  196. J. Craig Venter1
  1. 1 Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA.
  2. 2 Berkeley Drosophila Genome Project (BDGP), Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.
  3. 3 Human Genome Sequencing Center, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.
  4. 4 BDGP, Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA.
  5. 5 European Molecular Biology Laboratory (EMBL)–European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK.
  6. 6 Neomorphic Inc., 2612 Eighth Street, Berkeley, CA 94710, USA.
  7. 7 GenetixXpress Pty. Ltd., 78 Pacific Road, Palm Beach, Sydney, NSW 2108, Australia.
  8. 8 Department of Medical Informatics, IMIM–UPF C/Dr. Aiguader 80, 08003 Barcelona, Spain.
  9. 9 Department of Molecular and Cellular Biology, Harvard University, 16 Divinity Avenue, Cambridge, MA 02138, USA.
  10. 10 Department of Genetics, Box 8232, Washington University Medical School, 4566 Scott Avenue, St. Louis, MO 63110, USA.
  11. 11 Institute of Molecular Biology and Biotechnology, Forth, Heraklion, Greece.
  12. 12 European Drosophila Genome Project (EDGP), EMBL, Heidelberg, Germany.
  13. 13 Department of Molecular and Cell Biology, University of California, Berkeley, CA 94710, USA.
  14. 14 Genoscope, 2 rue Gaston Crémieux, 91000 Evry, France.
  15. 15 Section of Molecular and Cellular Biology, University of California, Davis, CA 95618, USA.
  16. 16 Department of Genetics, University of Cambridge, Cambridge CB2 3EH, UK.
  17. 17 EDGP, Rennes University Medical School, UPR 41 CNRS Recombinaisons Genetiques, Faculte de Medicine, 2 av. du Pr. Leon Bernard, 35043 Rennes Cedex, France.
  18. 18 Department of Genetics, Stanford University, Palo Alto, CA 94305, USA.
  19. 19 Department of Statistics, University of California, Berkeley, CA 94720, USA.
  20. 20 EDGP, Centro de Biologı́a Molecular Severo Ochoa, CSIC, Universidad Autónoma de Madrid, 28049 Madrid, Spain.
  21. 21 MBVL, Salk Institute, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA.
  22. 22 Department of Biochemistry and Center for Insect Science, University of Arizona, Tucson, AZ 85721, USA.
  23. 23 EDGP, Montpellier University Medical School, Institut de Genetique Humaine, CNRS (CRBM), 114 rue de la Cardonille, 34396 Montpellier Cedex 5, France.
  24. 24 Laboratory of Molecular Genetics, National Institute of Child Health and Human Development, National Institutes of Health (NIH), Bethesda, MD 20892, USA.
  25. 25 Department of Biology, McGill University, 1205 Avenue Docteur Penfield, Montreal, Quebec, Canada.
  26. 26 The Institute for Genomic Research, Rockville, MD 20850, USA.
  27. 27 Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, MD 20742, USA.
  28. 28 EDGP, Sanger Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK.
  29. 29 Department of Biochemistry, University of Tennessee, Memphis, TN 38163, USA.
  30. 30 EDGP, Department of Anatomy and Physiology, University of Dundee, Dundee DD1 4HN, UK, and Department of Biological Sciences, Open University, Milton Keynes MK7 6AA, UK.
  31. 31 HHMI/Embryology, Carnegie Institution of Washington, Baltimore, MD 21210, USA.
  32. 32 Motorola BioChip Systems, Tempe, AZ 85284, USA.
  33. 33 Cell Biology and Metabolism Branch, National Institute of Child Health and Human Development, NIH, Bethesda, MD 20892, USA.
  34. 34 Howard Hughes Medical Institute, BDGP, University of California, Berkeley, CA 94720, USA.
  1. *To whom correspondence should be addressed.

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