04 August 2000
Vol 289, Issue 5480

About The Cover

Cover image expansion

COVER The three-dimensional x-ray crystal structure of the light-sensitive protein rhodopsin, at 2.8 Å. Members of this family of seven-transmembrane helix G protein-coupled receptors detect environmental signals and transmit them to cells. The protein backbone is shown schematically with a transparent surface. The pigment that absorbs light, 11-cis-retinal (a derivative of vitamin A), is shown in green, and the carbohydrate moiety is blue. Shading is in red. See page 739. [Image: C. A. Behnke]