News FocusPharmacology

A Worrisome Side Effect of an Antianxiety Remedy

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Science  05 Jan 2001:
Vol. 291, Issue 5501, pp. 37
DOI: 10.1126/science.291.5501.37

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As reports came in on drug interactions with St. John's wort, the Food and Drug Administration issued an official warning to doctors and pharmacists noting that the herb could interfere with dozens of drugs, including the antiseizure medication phenobarbital, the breast cancer drug tamoxifen, the oral contraceptive ethinyl estradiol, and antiretrovirals used to treat AIDS.