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Structural Mechanism for Statin Inhibition of HMG-CoA Reductase

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Science  11 May 2001:
Vol. 292, Issue 5519, pp. 1160-1164
DOI: 10.1126/science.1059344

Article Information

vol. 292 no. 5519 1160-1164

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication January 26, 2001
  • Accepted for publication April 3, 2001
  • .

Author Information

  1. Eva S. Istvan1,
  2. Johann Deisenhofer1,2,*
  1. 1 Department of Biochemistry,
  2. 2 Howard Hughes Medical Institute, University of Texas Southwestern Medical Center at Dallas, TX 75390–9050, USA.

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