13 July 2001
Vol 293, Issue 5528

About The Cover

Cover image expansion

COVER Abnormal immunoglobulin deposits (green fluorescence) in a kidney glomerulus of a mouse with mutations in the genes encoding the closely related receptor tyrosine kinases Tyro 3, Axl, and Mer. These mice develop a severe lymphoproliferative autoimmune disease and generate self-reactive antibodies that attack a variety of tissues, including the kidney. 233 [Image: Q. Lu, G. Lemke]