News of the WeekGenomics

Taking Aim at Celera's Shotgun

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Science  08 Mar 2002:
Vol. 295, Issue 5561, pp. 1817
DOI: 10.1126/science.295.5561.1817b

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In a paper published in the 5 March online Proceedings of the National Academy of Sciences, three leaders of the publicly funded Human Genome Project assert that what appeared to be a dead-heat race to sequence the genome was actually nothing of the sort. Celera Genomics, the authors argue, broke down information from the public database into patterns that were easy to reassemble. The company's public relations machine then sold the effort as a triumph of the whole-genome shotgun approach, the authors add, making it appear different from the public frame-by-frame reading.