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Structure of an HIF-1α-pVHL Complex: Hydroxyproline Recognition in Signaling

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Science  07 Jun 2002:
Vol. 296, Issue 5574, pp. 1886-1889
DOI: 10.1126/science.1073440

Article Information

vol. 296 no. 5574 1886-1889

PubMed: 
Print ISSN: 
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History: 
  • Received for publication March 8, 2002
  • Accepted for publication May 1, 2002
  • .

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Author Information

  1. Jung-Hyun Min1,
  2. Haifeng Yang2,
  3. Mircea Ivan2,
  4. Frank Gertler4,
  5. William G. Kaelin Jr.2,3,
  6. Nikola P. Pavletich1,*
  1. 1 Cellular Biochemistry and Biophysics Program and Howard Hughes Medical Institute, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.
  2. 2 Dana-Farber Cancer Institute and
  3. 3 Howard Hughes Medical Institute, Harvard Medical School, Boston, MA 02115, USA.
  4. 4 Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

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