News of the WeekCancer Research

Nanoparticles Cut Tumors' Supply Lines

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Science  28 Jun 2002:
Vol. 296, Issue 5577, pp. 2314-2315
DOI: 10.1126/science.296.5577.2314b

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On page 2404, a team reports erasing tumors in mice by packing a tiny particle with a gene that forces blood vessel cells to self-destruct and then "mailing" the particle to blood vessels feeding tumors. Researchers are enthusiastic about the new work, although they are treading gingerly around the landmines in cancer treatment, where hopes have been raised and dashed many times.