26 July 2002
Vol 297, Issue 5581

About The Cover

Cover image expansion

COVER Electron micrograph showing a stalled DNA replication fork in a checkpoint-defective yeast mutant. Aberrant DNA replication is one mechanism postulated to contribute to genome instability. The molecular basis of genome instability and its role in cancer development are the subject of a special feature in this issue. See page 599 [Image: J. M. Sogo et al.]