DATABASE: Hunting Heavyweight Genes

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Science  26 Jul 2002:
Vol. 297, Issue 5581, pp. 483
DOI: 10.1126/science.297.5581.483c

The new Obesity Gene Map database feeds visitors the skinny on nearly 80 human genes thought to be involved in obesity. Bioinformatics guru Eric Snyder of the Pennington Biomedical Research Center in Baton Rouge, Louisiana, tends the site, an online version of a review his group publishes annually in Obesity Research. Listed are suspects and convicted culprits such as the gene for the blood- sugar regulator insulin and the gene for leptin, a hormone that governs body fat and appetite. Each entry summarizes the evidence linking the gene to obesity and lets you track down its chromosomal location, find nearby genes, and check the original references.

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