Gene Duplication and Evolution

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Science  09 Aug 2002:
Vol. 297, Issue 5583, pp. 945-947
DOI: 10.1126/science.1075472

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The duplication of short chromosomal segments in the genome may contribute to the formation of new species. In his Perspective, Lynch explores the potential implications of new work ( Bailey et al.) that calculates the number of segmental duplications in the human genome, as well as other recent comparative data on fine-scale changes in chromosomal architecture.