DATABASE: Dissecting the Cell's Power Plant

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Science  13 Sep 2002:
Vol. 297, Issue 5588, pp. 1775
DOI: 10.1126/science.297.5588.1775b

The mitochondria that fuel cellular activities tote their own set of genes, betraying their origins as bacterial interlopers. This genome database, sponsored by four German universities and institutions, boasts data on hundreds of mitochondrial genes and their proteins. Whether you're interested in humans, mice, or other model organisms, you can find sequence and function information for genes in the mitochondrial DNA and for related genes in the cell's nuclear DNA. The site also catalogs diseases triggered by mutations in these genes, and you can track down proteins by their function, location within the cell, and other attributes.

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