SOFTWARE: Get Your Chips in Order

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Science  27 Sep 2002:
Vol. 297, Issue 5590, pp. 2175
DOI: 10.1126/science.297.5590.2175d

Thanks to microarrays, or gene chips, measuring the activity of hundreds or even thousands of genes is routine. Thanks to microarrays, researchers often bog down in a morass of data, says Lao Saal. To help out, Saal and colleagues at the University of Lund in Sweden crafted BASE, database software that lets you store, categorize, and analyze information from gene-chip experiments. BASE works with commercially available and custom-made chips and can handle a range of data, from experimental protocols to images. Because BASE is open-source software, users can download it for free, make their own modifications, and share their improvements with other scientists through the Web site, says Saal, who is now a medical student at Columbia University.

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