News of the WeekClinical Research

Gene Therapy a Suspect in Leukemia-like Disease

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Science  04 Oct 2002:
Vol. 298, Issue 5591, pp. 34-35
DOI: 10.1126/science.298.5591.34

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French gene therapists reported this week that one of 10 children they treated for a lethal immune deficiency has developed a blood disorder resembling leukemia. Concerned that the gene therapy might have caused the problem, researchers have halted the trial and urged others who use similar methods to hold off until the risks are assessed. At press time, French regulatory officials were preparing a public advisory.