EXHIBITS: Orchestrating a Fly

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Science  18 Oct 2002:
Vol. 298, Issue 5593, pp. 501
DOI: 10.1126/science.298.5593.501e

Like musicians, the genes that mold a growing fly need to have exquisite timing. Starting or stopping at the wrong point can lead to discordant results. Researchers at the Berkeley Drosophila Genome Project have been reading the genetic score of fruit fly development by using RNA probes to tag parts of the embryo that express a particular gene. This new site holds digital images showing the activity patterns of 1354 of the fly's 13,600 genes. The report for each gene shows where the gene is turned on during different stages of development and also presents DNA microarray expression profiles. The site's creators plan to post new findings about every 3 months.


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