Special Reviews

Anterior-Posterior Polarity in C. elegans and Drosophila--PARallels and Differences

See allHide authors and affiliations

Science  06 Dec 2002:
Vol. 298, Issue 5600, pp. 1946-1950
DOI: 10.1126/science.1072162

You are currently viewing the abstract.

View Full Text

Log in to view the full text

Log in through your institution

Log in through your institution


The eggs of Caenorhabditis elegans andDrosophila bear little similarity to each other, yet both depend on the par genes for control of anterior-posterior polarity. Here we explore possible common roles for the pargenes (pars) in converting transient asymmetries into stably polarized axes. Although clear mechanistic parallels remain to be established, par-dependent regulation of microtubule dynamics and protein stability emerge as common themes.

  • * To whom correspondence should be addressed. E-mail: gseydoux{at}jhmi.edu

View Full Text

Stay Connected to Science