Where Do Male Genes Live?

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Science  31 Jan 2003:
Vol. 299, Issue 5607, pp. 670-671
DOI: 10.1126/science.1082030

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One might predict that in males, genes that are expressed in male-specific tissues such as the testis would be found on the single X chromosome (the Y chromosome containing very few functional genes). Not so, explains Schlötterer in his Perspective, which discusses new work showing that in the fruit fly male-biased genes are found predominantly on the autosomes and not on the X chromosome (Parisi et al.).