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Modulation of Heterochromatin Protein 1 Dynamics in Primary Mammalian Cells

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Science  31 Jan 2003:
Vol. 299, Issue 5607, pp. 719-721
DOI: 10.1126/science.1078694

Article Information

vol. 299 no. 5607 719-721

DOI: 
https://doi.org/10.1126/science.1078694
PubMed: 
12560554
Published By: 
American Association for the Advancement of Science
Print ISSN: 
0036-8075
Online ISSN: 
1095-9203
History: 
  • Received for publication September 23, 2002
  • Accepted for publication December 13, 2002
  • .

Author Information

  1. Richard Festenstein1,*,
  2. Stamatis N. Pagakis2,
  3. Kyoko Hiragami1,
  4. Debbie Lyon3,
  5. Alain Verreault3,
  6. Belaid Sekkali4,
  7. Dimitris Kioussis4
  1. 1 CSC Gene Control Mechanisms and Disease Group, Division of Medicine, Imperial College School of Medicine, Hammersmith Campus, Du Cane Road, London W12 ONN, UK.
  2. 2 Confocal and Image Analysis Laboratory, National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, UK.
  3. 3 Chromosome Dynamics Laboratory, Cancer Research UK, London Research Institute, Clare Hall Laboratories, Blanche Lane, South Mimms, Potters Bar, Hertfordshire EN6 3LD, UK.
  4. 4 Division of Molecular Immunology, National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, UK.

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  • Modulation of Heterochromatin Protein 1 Dynamics in Primary Mammalian Cells

    By Richard Festenstein, Stamatis N. Pagakis, Kyoko Hiragami, Debbie Lyon, Alain Verreault, Belaid Sekkali, Dimitris Kioussis

    Science : 719-721

    Heterochromatin dynamically regulates access of other molecules to DNA, rather than serving only as a static barrier.

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