Figures
Fig. 1. Phylogenetic analysis of SARS proteins. Unrooted phylogenetic trees were generated by clustalw 1.74 (33) using the BLOSUM comparison matrix and a bootstrap analysis of 1000 iterations. Numbers indicate bootstrap replicates supporting each node. Phylogenetic trees were drawn with the Phylip Drawtree program 3.6a3 (34). Branch lengths indicate the number of substitutions per residue. GenBank accession numbers for protein sequences are as follows: (A) Replicase 1A: BCoV (bovine coronavirus), AAL40396; HCoV-229E (human coronavirus), NP_073555; MHV (mouse hepatitis virus), NP_045298; IBV (avian infectious bronchitis virus), CAC39113; TGEV (porcine transmissible gastroenteritis virus), NP_058423. (B) Membrane glycoprotein: PHEV (porcine hemagglutinating encephalomyelitis virus), AAL80035; BCoV, NP_150082; IBV 1, AAF35863; IBV 2, AAK83027; MHV, AAF36439; TGEV, NP_058427; HCoV-OC43, AAA45462; FCoV (feline coronavirus), BAC01160. (C) Nucleocapsid: MHV, P18446; BCoV, NP_150083; IBV 1, AAK27162; IBV 2, NP_040838; FCoV, CAA74230; PTGV (porcine transmissible gastroenteritis virus), AAM97563; HCoV-229E, NP_073556; HCoV-OC43, P33469; PHEV, AAL80036; TCV (turkey coronavirus), AAF23873. (D) S (Spike) protein: BCoV, AAL40400; MHV, P11225; HCoV-OC43, S44241; HCoV-229E, AAK32191; PHEV, AAL80031; PRCoV (porcine respiratory coronavirus), AAA46905; PEDV (porcine epidemic diarrhea virus), CAA80971; CCoV (canine coronavirus), S41453; FIPV (feline infectious peritonitis virus), BAA06805; IBV, AAO34396.
Tables
Supporting Online Material
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Materials and Methods
References