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Science  13 Jun 2003:
Vol. 300, Issue 5626, pp. 1657
DOI: 10.1126/science.300.5626.1657b

An ad hoc investigatory committee at the University of North Carolina at Chapel Hill has found that the last author (S.A.L.) of the paper “BRCA1 required for transcription-coupled repair of oxidative DNA damage” (1) has “fabricated and falsified research findings,” and this paper has been implicated. The last author disputes this finding of the ad hoc committee. Although some findings in the paper, notably those in Fig. 4, are valid, the overall integrity of the paper cannot be supported, and it should be retracted. The first four authors of the paper have not been implicated in any way. L.C.G., A.M.L., and B.H.K. can certify the quality of the cells used in all of these experiments and are willing to provide them to other investigators who would like to address the role of BRCA1 in transcription-coupled repair.


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