PerspectiveStructural Biology

Breaching the Barrier

See allHide authors and affiliations

Science  01 Aug 2003:
Vol. 301, Issue 5633, pp. 603-604
DOI: 10.1126/science.1088621

You are currently viewing the summary.

View Full Text

Log in to view the full text

Log in through your institution

Log in through your institution


There are a huge number of membrane transporter proteins that transport molecules across the impermeable barrier presented by cellular membranes. In their Perspective, Locher et al. discuss a double tour de force ( Abramson et al., Huang et al.), which provide structural determinations of two bacterial transporters, LacY and GlpT, and insights into how they work.