DATABASE: Microbial Genomes Galore

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Science  17 Oct 2003:
Vol. 302, Issue 5644, pp. 367
DOI: 10.1126/science.302.5644.367e

A mere 8 years ago, molecular biologists sequenced the genome of an organism for the first time—the nose-dwelling bacterium Haemophilus influenzae. Now that even the human genome has been completed, whole-organism sequences are pouring out of labs. GeneDB, sponsored by the U.K.'s Wellcome Trust Sanger Institute, lets you analyze partial and complete genomes for 14 often disease-causing bacteria, protozoans, and fungi, including Schizosaccharomyces pombe, a relative of the widely studied brewer's yeast, and Trypanosoma brucei, a squiggly parasite that causes African sleeping sickness. GeneDB offers the familiar searching tools, allowing you to track down sequences for a particular creature or compare DNA among organisms. The curators plan to add data on gene expression and protein interactions.

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