News of the WeekCancer Research

Drug Candidate Bolsters Cell's Tumor Defenses

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Science  02 Jan 2004:
Vol. 303, Issue 5654, pp. 23-25
DOI: 10.1126/science.303.5654.23a

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In work published online by Science this week (, a research team identifies a class of small molecules that can turn the activity of the p53 tumor-suppressor gene, which is inactivated in most human cancers, back on. They may thus be good candidates for drugs that shrink cancerous tumors.