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Uracil DNA Glycosylase Activity Is Dispensable for Immunoglobulin Class Switch

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Science  20 Aug 2004:
Vol. 305, Issue 5687, pp. 1160-1163
DOI: 10.1126/science.1098444

Article Information

vol. 305 no. 5687 1160-1163

PubMed: 
Print ISSN: 
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History: 
  • Received for publication March 29, 2004
  • Accepted for publication July 12, 2004

Author Information

  1. Nasim A. Begum1,
  2. Kazuo Kinoshita1,
  3. Naoki Kakazu2,
  4. Masamichi Muramatsu1,
  5. Hitoshi Nagaoka1,
  6. Reiko Shinkura1,
  7. Detlev Biniszkiewicz3,
  8. Laurie A. Boyer3,
  9. Rudolf Jaenisch3,
  10. Tasuku Honjo1,*
  1. 1 Department of Medical Chemistry and Molecular Biology, Graduate School of Medicine, Kyoto University, Yoshida Sakyo-ku, Kyoto 606-8501, Japan.
  2. 2 Department of Molecular-Targeting Cancer Prevention, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kajii-cho, Kamigyo-ku, Kyoto 602-8566, Japan.
  3. 3 Whitehead Institute for Biomedical Research, 9 Cambridge Center, Cambridge, MA 02142, USA.
  1. * To whom correspondence should be addressed. E-mail: honjo{at}mfour.med.kyoto-u.ac.jp

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