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Evidence for Positive Epistasis in HIV-1

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Science  26 Nov 2004:
Vol. 306, Issue 5701, pp. 1547-1550
DOI: 10.1126/science.1101786

Article Information

vol. 306 no. 5701 1547-1550

PubMed: 
Print ISSN: 
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History: 
  • Received for publication June 22, 2004
  • Accepted for publication October 14, 2004

Author Information

  1. Sebastian Bonhoeffer1,*,
  2. Colombe Chappey2,
  3. Neil T. Parkin2,
  4. Jeanette M. Whitcomb2,
  5. Christos J. Petropoulos2
  1. 1 Ecology and Evolution, ETH Zurich, ETH Zentrum NW, CH-8092 Zurich, Switzerland.
  2. 2 ViroLogic, 345 Oyster Point Boulevard, South San Francisco, CA 94080–1913, USA.
  1. * To whom correspondence should be addressed. E-mail: seb{at}env.ethz.ch
  • Note added in proof: After this paper had been accepted, a related paper or epistasis in the vesicular stomatitis virus by Sanjuán et al. appeared (29).

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