14 January 2005
Vol 307, Issue 5707

About The Cover

Cover image expansion

COVER The enzyme adenosine triphosphate (ATP) synthase spanning a bacterial cell membrane. A promising new diarylquinoline drug interacts with the transmembrane portion of this enzyme in the bacteria that cause tuberculosis, killing the microbe by shutting down ATP synthesis. See page 223. [Image: W. Junge and MediTech Media]