04 March 2005
Vol 307, Issue 5714

About The Cover

Cover image expansion

COVER Artist's view of a human T cell as a globe, with the chemokine CCL3L1 shielding the cell from infection by HIV-1 (circles with red spikes) by virtue of its interaction with the HIV coreceptor CCR5 (yellow). CCL3L1 is represented by green circles emanating from green bands on chromosome 17, with the intensity indicating differences in gene dose (fluorescence in situ hybridization courtesy of Robin Leach). See page 1434. [Image: S. K. Ahuja and D. Baker]