18 March 2005
Vol 307, Issue 5716

About The Cover

Cover image expansion

COVER Repeated images of an optical cross section through a Drosophila wing epithelium very early in development, illustrating that regions lacking a morphogenetic signal (deprived regions shown in blue) also lack a well-organized apical cytoskeleton (yellow band, microtubules and F-actin together). As described on page 1785, extracellular signaling pathways can direct appendage development through position-specific effects on epithelial architecture. [Image: M. Gibson]