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Structural Bioinformatics-Based Design of Selective, Irreversible Kinase Inhibitors

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Science  27 May 2005:
Vol. 308, Issue 5726, pp. 1318-1321
DOI: 10.1126/science1108367

Article Information

vol. 308 no. 5726 1318-1321

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication December 6, 2004
  • Accepted for publication February 23, 2005
  • .

Author Information

  1. Michael S. Cohen,
  2. Chao Zhang,
  3. Kevan M. Shokat,
  4. Jack Taunton*
  1. Program in Chemistry and Chemical Biology, and Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA 94143-2280, USA.
  1. * To whom correspondence should be addressed. E-mail: taunton{at}cmp.ucsf.edu

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