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Extension of Murine Life Span by Overexpression of Catalase Targeted to Mitochondria

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Science  24 Jun 2005:
Vol. 308, Issue 5730, pp. 1909-1911
DOI: 10.1126/science.1106653

Article Information

vol. 308 no. 5730 1909-1911

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Print ISSN: 
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History: 
  • Received for publication October 22, 2004
  • Accepted for publication April 15, 2005

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Author Information

  1. Samuel E. Schriner1,5,
  2. Nancy J. Linford2,
  3. George M. Martin1,2,
  4. Piper Treuting3,
  5. Charles E. Ogburn2,
  6. Mary Emond4,
  7. Pinar E. Coskun5,
  8. Warren Ladiges3,
  9. Norman Wolf2,
  10. Holly Van Remmen6,
  11. Douglas C. Wallace5,
  12. Peter S. Rabinovitch2,*
  1. 1 Department of Genome Sciences, University of Washington, Seattle, WA 91895, USA.
  2. 2 Department of Pathology, University of Washington, Seattle, WA 91895, USA.
  3. 3 Department of Comparative Medicine, University of Washington, Seattle, WA 91895, USA.
  4. 4 Department of Biostatistics, University of Washington, Seattle, WA 91895, USA.
  5. 5 Center for Molecular and Mitochondrial Medicine and Genetics, Department of Biological Chemistry and Department of Ecology and Evolutionary Biology, University of California, Irvine, Irvine, CA 92697, USA.
  6. 6 Department of Cellular and Structural Biology, University of Texas Health Sciences Center at San Antonio, San Antonio, TX 78229, USA.
  1. * To whom correspondence should be addressed. E-mail: petersr{at}u.washington.edu

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