Research Article

Suppression of Aging in Mice by the Hormone Klotho

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Science  16 Sep 2005:
Vol. 309, Issue 5742, pp. 1829-1833
DOI: 10.1126/science.1112766

Article Information

vol. 309 no. 5742 1829-1833

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History: 
  • Received for publication March 25, 2005
  • Accepted for publication August 4, 2005

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Author Information

  1. Hiroshi Kurosu1,
  2. Masaya Yamamoto1,
  3. Jeremy D. Clark1,
  4. Johanne V. Pastor1,
  5. Animesh Nandi1,
  6. Prem Gurnani1,
  7. Owen P. McGuinness3,
  8. Hirotaka Chikuda4,
  9. Masayuki Yamaguchi4,
  10. Hiroshi Kawaguchi4,
  11. Iichiro Shimomura5,
  12. Yoshiharu Takayama2,
  13. Joachim Herz2,
  14. C. Ronald Kahn6,
  15. Kevin P. Rosenblatt1,
  16. Makoto Kuro-o1,*
  1. 1 Department of Pathology, University of Texas (UT) Southwestern Medical Center at Dallas, 5323 Harry Hines Bouleuvard, Dallas, TX 75390-9072, USA.
  2. 2 Department of Molecular Genetics, University of Texas (UT) Southwestern Medical Center at Dallas, 5323 Harry Hines Bouleuvard, Dallas, TX 75390-9072, USA.
  3. 3 Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, 702 Light Hall, Nashville, Tennessee 37232-0615, USA.
  4. 4 Department of Sensory and Motor System Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo, Tokyo 113-8655, Japan.
  5. 5 Department of Internal Medicine and Molecular Science, Graduate School of Medicine, Osaka University, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan.
  6. 6 Research Division, Joslin Diabetes Center, Department of Medicine, Harvard Medical School, One Joslin Place, Boston, MA 02215, USA.
  1. * To whom correspondence should be addressed. E-mail: makoto.kuro-o{at}utsouthwestern.edu
  • Published online 25 August 2005;

  • Include this information when citing this paper.

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