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Identification and Functional Characterization of Brainstem Cannabinoid CB2 Receptors

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Science  14 Oct 2005:
Vol. 310, Issue 5746, pp. 329-332
DOI: 10.1126/science.1115740

Article Information

vol. 310 no. 5746 329-332

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History: 
  • Received for publication June 6, 2005
  • Accepted for publication September 9, 2005
  • .

Author Information

  1. Marja D. Van Sickle1,*,
  2. Marnie Duncan1,*,
  3. Philip J. Kingsley2,
  4. Abdeslam Mouihate1,
  5. Paolo Urbani3,
  6. Ken Mackie4,
  7. Nephi Stella5,
  8. Alexandros Makriyannis6,
  9. Daniele Piomelli7,
  10. Joseph S. Davison1,
  11. Lawrence J. Marnett2,
  12. Vincenzo Di Marzo3,
  13. Quentin J. Pittman1,
  14. Kamala D. Patel1,
  15. Keith A. Sharkey1,
  1. 1 Institute of Infection, Immunity, and Inflammation and Hotchkiss Brain Institute, Department of Physiology and Biophysics, University of Calgary, Calgary, AB, Canada T2N 4N1.
  2. 2 Department of Biochemistry, Vanderbilt Institute of Chemical Biology, Center in Molecular Toxicology, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37232–0146, USA.
  3. 3 Endocannabinoid Research Group, Institute of Biomolecular Chemistry, Consiglio Nazionale delle Ricerche, Pozzuoli, Naples, Italy.
  4. 4 Department of Anesthesiology and Department of Physiology and Biophysics, University of Washington, Seattle, WA 98195–6540, USA.
  5. 5 Department of Pharmacology, Psychiatry, and Behavioral Sciences, University of Washington, Seattle, WA 98195–7280, USA.
  6. 6 Center for Drug Discovery, Department of Pharmaceutical Sciences, Northeastern University, Boston, MA 02115, USA.
  7. 7 Department of Pharmacology, Gillespie Neuroscience Facility, University of California, Irvine, CA 92697–6180, USA.
  1. To whom correspondence should be addressed. E-mail: ksharkey{at}ucalgary.ca
  • * These authors contributed equally to this work.

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