PerspectiveDevelopmental Biology

Less Steroids Make Bigger Flies

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Science  28 Oct 2005:
Vol. 310, Issue 5748, pp. 630-631
DOI: 10.1126/science.1120410

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Kirst King-Jones and Carl S. Thummel It has long been known that animal growth is achieved primarily during juvenile stages and terminates after sexual maturation. In their Perspective, King-Jones and Thummel discuss how the findings of Colombani et al. in this issue provide important new insights into how this coordination of growth and maturation is achieved through steroid and insulin signaling pathways.