03 March 2006
Vol 311, Issue 5765

About The Cover

Cover image expansion

COVER The enzymes that catalyze fatty acid formation are large protein complexes with multiple active sites. The architecture of the mammalian multienzyme (catalytic domains in various colors) is quite different from that of the fungal fatty acid synthase (in gray). Nonetheless, they catalyze the same conserved reaction pathway. See pages 1258 and 1263. Image: S. Jenni and T. Maier