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Toll-Like Receptor Triggering of a Vitamin D-Mediated Human Antimicrobial Response

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Science  24 Mar 2006:
Vol. 311, Issue 5768, pp. 1770-1773
DOI: 10.1126/science.1123933

Article Information

vol. 311 no. 5768 1770-1773

PubMed: 
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History: 
  • Received for publication December 16, 2005
  • Accepted for publication February 8, 2006

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Author Information

  1. Philip T. Liu1,2,*,
  2. Steffen Stenger4,*,
  3. Huiying Li3,
  4. Linda Wenzel4,
  5. Belinda H. Tan1,2,
  6. Stephan R. Krutzik2,
  7. Maria Teresa Ochoa2,
  8. Jürgen Schauber5,
  9. Kent Wu1,
  10. Christoph Meinken4,
  11. Diane L. Kamen6,
  12. Manfred Wagner7,
  13. Robert Bals8,
  14. Andreas Steinmeyer9,
  15. Ulrich Zügel10,
  16. Richard L. Gallo5,
  17. David Eisenberg3,
  18. Martin Hewison11,
  19. Bruce W. Hollis12,
  20. John S. Adams11,
  21. Barry R. Bloom13,
  22. Robert L. Modlin1,2,
  1. 1 Department of Microbiology, Immunology, and Molecular Genetics; University of California at Los Angeles, Los Angeles, CA 90095, USA.
  2. 2 Division of Dermatology, Department of Medicine, David Geffen School of Medicine; University of California at Los Angeles, Los Angeles, CA 90095, USA.
  3. 3 Department of Chemistry and Biological Chemistry, Howard Hughes Medical Institute; and Department of Energy Institute of Genomics and Proteomics, University of California at Los Angeles, Los Angeles, CA 90095, USA.
  4. 4 Institut für Klinische Mikrobiologie, Immunologie, und Hygiene, Universität Erlangen, D-91054 Erlangen, Germany.
  5. 5 Division of Dermatology, University of California at San Diego, and Veterans Affairs San Diego Healthcare Center, San Diego, CA 92161, USA.
  6. 6 Department of Medicine, Medical University of South Carolina (MUSC), Charleston, SC 29425, USA.
  7. 7 Klinikum Nürnberg, Medizinische Klinik 3, D-90340 Nürnberg, Germany.
  8. 8 Pneumologie, Universität Marburg, D-35043 Marburg, Germany.
  9. 9 Medicinal Chemistry, Schering AG, D-13342 Berlin, Germany.
  10. 10 Corporate Research Business Area (CRBA) Dermatology, Schering AG, D-13342 Berlin, Germany.
  11. 11 Department of Medicine, Division of Endocrinology, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
  12. 12 Departments of Pediatrics, Biochemistry, and Molecular Biology, MUSC, Charleston, SC 29425, USA.
  13. 13 Harvard School of Public Health, Boston, MA 02115, USA.
  1. To whom correspondence should be addressed. E-mail: rmodlin{at}mednet.ucla.edu
  • * These authors contributed equally to this work.

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