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Darwinian Evolution Can Follow Only Very Few Mutational Paths to Fitter Proteins

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Science  07 Apr 2006:
Vol. 312, Issue 5770, pp. 111-114
DOI: 10.1126/science.1123539

Article Information

vol. 312 no. 5770 111-114

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History: 
  • Received for publication December 7, 2005
  • Accepted for publication February 28, 2006
  • .

Author Information

  1. Daniel M. Weinreich*,
  2. Nigel F. Delaney,
  3. Mark A. DePristo,
  4. Daniel L. Hartl
  1. Department of Organismic and Evolutionary Biology, Harvard University, 16 Divinity Avenue, Cambridge, MA 02138, USA.
  1. * To whom correspondence should be addressed. E-mail: dmw{at}post.harvard.edu
  • Present address: Integrative Oceanography Division, Scripps Institute of Oceanography, 9500 Gilman Drive, La Jolla, CA 92037, USA.

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