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A Common Genetic Variant Is Associated with Adult and Childhood Obesity

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Science  14 Apr 2006:
Vol. 312, Issue 5771, pp. 279-283
DOI: 10.1126/science.1124779

Article Information

vol. 312 no. 5771 279-283

PubMed: 
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History: 
  • Received for publication January 10, 2006
  • Accepted for publication March 14, 2006
  • .

Author Information

  1. Alan Herbert1,*,
  2. Norman P. Gerry1,
  3. Matthew B. McQueen2,
  4. Iris M. Heid3,4,
  5. Arne Pfeufer5,6,
  6. Thomas Illig3,4,
  7. H.-Erich Wichmann3,4,7,
  8. Thomas Meitinger5,6,
  9. David Hunter2,8,9,
  10. Frank B. Hu2,8,9,
  11. Graham Colditz8,9,
  12. Anke Hinney10,
  13. Johannes Hebebrand10,
  14. Kerstin Koberwitz6,10,
  15. Xiaofeng Zhu11,
  16. Richard Cooper11,
  17. Kristin Ardlie12,
  18. Helen Lyon13,14,15,
  19. Joel N. Hirschhorn13,14,15,
  20. Nan M. Laird16,
  21. Marc E. Lenburg1,
  22. Christoph Lange9,13,
  23. Michael F. Christman1,*
  1. 1 Department of Genetics and Genomics, Boston University Medical School, E613, 715 Albany Street, Boston, MA 02118, USA.
  2. 2 Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA.
  3. 3 Institute of Epidemiology, Forschungszentrum für Umwelt und Gesundheit, D-85764 Neuherberg, Germany.
  4. 4 KORA Group, Forschungszentrum für Umwelt und Gesundheit, D-85764 Neuherberg, Germany.
  5. 5 Institute of Human Genetics, Forschungszentrum für Umwelt und Gesundheit, D-85764 Neuherberg, Germany.
  6. 6 Institute of Human Genetics, Technical University Munich, D-81671 Munich, Germany.
  7. 7 Institute for Medical Informatics, Biometry and Epidemiology, Ludwig Maximilians University, Munich, Germany.
  8. 8 Nurses Health Study, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA.
  9. 9 Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA.
  10. 10 Department of Child and Adolescent Psychiatry of the University of Duisburg-Essen, D-45147 Essen, Germany.
  11. 11 Department of Preventive Medicine and Epidemiology, Loyola University Medical Center, Maywood, IL 60153, USA.
  12. 12 Genomics Collaborative, SeraCare Life Sciences, Cambridge, MA, USA.
  13. 13 Program in Genomics and Divisions of Genetics and Endocrinology, Children's Hospital, Boston, MA 02115, USA.
  14. 14 Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.
  15. 15 Broad Institute of Harvard and MIT, Cambridge, MA 02139, USA.
  16. 16 Department of Biostatistics, Harvard School of Public Health, 655 Huntington Avenue, Boston, MA 02115, USA.
  1. * To whom correspondence should be addressed. E-mail: aherbert{at}bu.edu (A.H.); mfc{at}bu.edu (M.F.C.)

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